In Zakynthos about 100 important species have been recorded of which 30 are characterized as Greek endemics and 13 as sub-endemics (limited distribution in Greece and met in another country i.e., Crocus boryi) or Balkan endemic (i.e. Fritillaria messanensis subsp. gracilis) and 3 exclusively endemic species.
In the protected area, the corresponding numbers modulate to 53 important species, 18 Greek endemics and 7 sub-endemics, and also 3 exclusively endemic species in Zakynthos island. From the recorded species 35 are subjected in a protection scheme, including the exclusively endemic species of Zante (Asperula naufraga - endangered, Limonium phitosianum - vulnerable, Limonium zacynthium – vulnerable) and Arenaria peloponnesiaca (vulnerable).
47 species of orchids and cyclamens expand to various areas and four of them are rare or almost endangered in Greece (Ophrys reinholdii, Ophrys ferrum-equinum subsp. gottfriediana, Orchis laxiflora, Orchis palustris). In addition, the local endemic species Serapias ionica, has been classified as «almost endangered» (NT– IUCN).